diff --git a/docker/rootfs/etc/s6-overlay/s6-rc.d/prepare/20-paths.sh b/docker/rootfs/etc/s6-overlay/s6-rc.d/prepare/20-paths.sh
index 2f59ef41a..ebbcd958c 100755
--- a/docker/rootfs/etc/s6-overlay/s6-rc.d/prepare/20-paths.sh
+++ b/docker/rootfs/etc/s6-overlay/s6-rc.d/prepare/20-paths.sh
@@ -39,3 +39,7 @@ touch /var/log/nginx/error.log || true
 chmod 777 /var/log/nginx/error.log || true
 chmod -R 777 /var/cache/nginx || true
 chmod 644 /etc/logrotate.d/nginx-proxy-manager
+
+# nginx has not been started yet, so any pid file here is stale. Remove it,
+# otherwise a pid file owned by another user stops nginx starting as PUID:PGID
+rm -f /run/nginx/nginx.pid